It's out in 2019
It's an Unreal Engine 4 game
Your protagonist isn't voiced
There's a special class of "science weapons" that will have special, ridiculous effects, like a shrink ray
There's a full character creator even though it's first-person only (you'll see your character in the inventory, and if you leave the game idling long)
Your companions don't have separate inventories. Taking companions with you just gives you more inventory space to work with yourself
If companions really dislike the decisions you make, they'll leave and go back to the ship. You can persuade them to see things your way
No romancing companions. They considered it, but decided against it.
Companions each have a special attack (one named Felix does a double drop kick) but you can also equip them with whatever weapons you want
Hacking and lockpicking don't have minigames, and are simply based on your attributes
There are six skills (strength, intelligence etc.) and for every 20 points you put into one (up until 100) you'll gain a new perk
As in the creators' past games, you can play as a "dumb" character with stupid dialogue options. Your companions react appropriately.
They're still not sure if it will be possible to play through the game completely pacifist (but you'll almost definitely have to at least kill some robots)
Robots aren't sentient, but your ship's AI seems to have a strange degree of personality
Tim Cain wants you to know there are a lot of drugs, but he's not going to pressure you to take them